When people think about nutrition, too often they focus on what they eat in terms of protein, carbs and calories.
But the oils you cook with every single day may be just as important, if not more so, for your long-term health.
The cooking oils you use regularly directly influence:
Cardiovascular risk
Metabolic health
Oxidative stress in the body
Mitochondrial function
And ultimately, how fast you age
Some oils actively protect your cells, whilst others quietly accelerate aging through chronic inflammation.
In this guide, we break down the science behind the most commonly used oils today — with a specific focus on the increasingly searched comparison:
What is best - extra virgin olive oil vs avocado oil vs seed oils?
So which oil is actually a good oil for heart health and longevity — and which should you try to avoid?
When comparing extra virgin olive oil vs avocado oil, olive oil consistently comes out ahead for long-term health.
Extra virgin olive oil (EVOO) is extracted primarily through cold pressing. This is a mechanical method that converts fresh olives into oil with minimal processing that doesnt use heat or chemicals.
This process helps to preserve high levels of monunsaturated fats, antioxidants and polyphenols - the sources of its many health benefits.
The hype about EVOO isn’t just marketing or the latest health fad — extra virgin olive oil is one of the most studied foods in nutritional science.
The monunsaturdated fats in extra virgin olive oil (EVOO) are made up mostly of oleic acid.
This is a monounsaturated fat that:
Improves cholesterol balance
Reduces LDL oxidation
Supports blood vessel health
Regular consumption of EVOO is linked to a 9% lower risk of heart disease and an 11% decreased risk in all cause mortality. This makes EVOO one of the best oils for heart health available.
What truly separates EVOO from avocado oil and seed oils is its high polyphenol content.
High-quality EVOO contains over 30 bioactive compounds; including hydroxytyrosol, oleuropein and tyrosol.
These polyphenols help to reduce chronic inflammation and protect your mitochondria (the cells powerhouses). They slow aging at a cellular level and also improve endothelial function (which controls the blood vessels constriction and dilation, blood clotting and inflammation.)
If you’re searching for the best olive oil for health polyphenols, the most important factors are freshness and quality. One of our favourites is Kirkland Organic Extra Virign Olive Oil.
The Mediterranean diet — one of the most consistently studied and highest rated longevity diets — is built on a foundation of olive oil.
The Mediterranean diet is associated with:
A lower risk of cardiovascular disease
Reduced stroke risk
Improved metabolic health
Lower inflammatory markers (CRP, IL-6)
Olive oil is the dietary foundation that ties these benefits together.
EVOO is widely supported by research as a food that promotes blood sugar regulation and metabolic health.
This helps to:
Blunt post-meal glucose spikes
Improve insulin sensitivity
Support metabolic flexibility
This is critical for preventing type 2 diabetes and age-related metabolic decline.
NSAIDS (Nonsteroidal Anti-Inflammatory Drugs) are common medications such as aspirin and ibuprofen, that are used to treat ailments such as pain, fever and inflammation.
They also have a number of potential downsides with long term or high dose use, such as gastrointestinal issues, cardiovascualr risk and kidney damage.
Oleocanthal in olive oil acts as a natural anti-inflammatory drug that inhibits inflammatory pathways. This reduces the key drivers of aging and chronic disease, without the negative risks of NSAIDS.
Extra Virgin Olive Oil is a very versatile product. Recommended uses include:
Daily cooking (low–medium heat)
Salad dressings
Drizzling and finishing
Everyday longevity oil
It has a smoke point of around 375°F or 190°C, and is far more heat-stable than most people believe due to its high levels of antioxidants.
In the debate of extra virgin olive oil vs avocado oil, avocado oil performs well — but for different reasons than EVOO.
Like olive oil, avocado oil supports heart and metabolic health through its high levels of monunsaturated fats.
With one of the highest smoke points of plant based oils of around 480°F / 250°C, avocado oil is one of the best options for:
Roasting
Pan-searing
Baking
It also has a neutral, mild flavour that won't overpower food.
Avocado oil is a nutrient dense oil that is rich in antioxidants. It provides lutein which helps to support eye health, plus vitamin E and other nutrients that protect the cells from oxidative damage.
A UC Davis study found that over 60% of avocado oils on the market were rancid, oxidised or mixed with other oils or additives.
This calls into question the quality of the avocado oil generally available. If you use avocado oil, brand trust matters more than almost anything else.
Due to its high smoke point, the best uses for avocado oil are for:
High-heat cooking
Roasting vegetables
Occasional frying
When people compare olive oil vs seed oil, the difference is stark.
Compared to the minimum cold pressing extraction of extra virgin olive oil, seed oils are mostly extracted from seeds using a combination of high heat and chemical solvent extraction. This strips them of their nutrients and adds harmful ingredients.
This process leads to a high omega-6 content and potential oxidation which is also linked to causing chronic inflammation. There are also increased risks of diseases such as cardiovascular disease, type 2 diabetes, non-alcoholic fatty liver disease and some forms of cancer.
Seed oils include:
Soybean
Sunflower
Safflower
Corn
Canola
Grapeseed
These are industrially produced oils rather than traditional foods and are common in fried fast foods, processed snacks (chips, cookies, crackers), margarine and baked goods.
Seed oils are extremely high in omega-6 polyunsaturated fats (PUFAs). In contrast to the healthy omega-3 fatty acids which are anti-inflammatory and support brain and heart health, omega-6's are pro-inflammatory.
Whilst still an essential oil for cellular function, the most important factor is the balance between the two.
Modern diets often reach an omega-6:3 ratio of 15–20:1, while longevity research suggests closer to 2–4:1 is optimal for long term health.
PUFAs in seed oils oxidise easily under heat, light and storage. This produces aldehydes, lipid peroxides and trans fats.
These damage DNA, mitochondria and blood vessels.
High seed oil intake is linked to increased inflammation in the body.
Chronic inflammation is one of the core drivers of aging.
Seed oils should ideally be avoided, but if used you should look for cold-pressed varieites, with minimal amounts and no high heat.
| Feature | Olive Oil (EVOO) | Avocado Oil | Seed Oils |
|---|---|---|---|
| Heart health | ⭐⭐⭐⭐⭐ | ⭐⭐⭐⭐ | ⭐ |
| Polyphenols | ⭐⭐⭐⭐⭐ | ⭐⭐ | ⭐ |
| Heat stability | ⭐⭐⭐⭐ | ⭐⭐⭐⭐⭐ | ⭐ |
| Inflammation | ↓↓↓ | ↓↓ | ↑↑↑ |
| Longevity evidence | ⭐⭐⭐⭐⭐ | ⭐⭐ | ⭐ |
EVOO is supported by the strongest evidence and contains the highest polyphenol levels. This is the best option for cardiovascular protection.
Avocado Oil - but aim to use trusted brands only to ensure the efficacy of the product.
Industrial seed oils such as canola, sunflower, soybean and corn oils.
In your daily routine, use EVOO generously for cooking, dressings and finishing salads.
Avocado oil can be used sparingly for high heat cooking such as roasting. Avoid or minimise use of vegetable oils, fried restaurant foodsor “light” or refined olive oils.
Is extra virgin olive oil better than avocado oil?
Yes — for longevity, heart health and anti-inflammatory effects - extra virgin olive oil is superior.
What is the best olive oil for health polyphenols?
Fresh, cold-pressed, extra virgin olive oil with a peppery or bitter taste.
Is olive oil better than seed oil?
Yes. Olive oil is far more stable, and offers a number of anti-inflammatory and health protective benefits.
What’s the healthiest cooking oil?
EVOO for daily use, avocado oil for high heat.
The oils you use every day aren’t neutral — they send biochemical signals every day.
The science is clear:
Extra virgin olive oil is the best oil for health
Avocado oil is useful but secondary to EVOO
Seed oils accelerate inflammation and aging
The small daily choices that you make compound either positively - or negatively for your long term health.
Choose oils that support your heart, cells, and longevity — not ones that quietly work against you.
SIGN UP TO GET FREE WEEKLY INSIGHTS IN OUR NEWSLETTER

Evidence-based strategies to lower your biological age and optimize your healthspan — without the guesswork.
Some posts may contain affiliate links, which means we may earn a small commission - at no additional cost to you - if you make a purchase through those links. Thanks for your support. Read our full affiliate disclosure here.
Educational content only. Not medical advice.
support@lifespanblueprint.com
Follow us
Newsletter
Join 10,000+ longevity seekers and get weekly science-backed strategies to live younger, longer.
Enter your email below to get the free guide '7 Longevity Hacks You Can Start Today' instantly.
Created with © systeme.io